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TRPC1/5-Ca(V)3 Complex Mediates Leptin-Induced Excitability in Hypothalamic Neurons
Leptin regulates hypothalamic POMC(+) (pro-opiomelanocortin) neurons by inducing TRPC (Transient Receptor Potential Cation) channel-mediate membrane depolarization. The role of TRPC channels in POMC neuron excitability is clearly established; however, it remains unknown whether their activity alone...
Autores principales: | Perissinotti, Paula P., Martínez-Hernández, Elizabeth, Piedras-Rentería, Erika S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226082/ https://www.ncbi.nlm.nih.gov/pubmed/34177455 http://dx.doi.org/10.3389/fnins.2021.679078 |
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