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Germline Variants and Genetic Interactions of Several EMT Regulatory Genes Increase the Risk of HBV-Related Hepatocellular Carcinoma

Epithelial-mesenchymal transition (EMT) plays an important role in the development of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). We hypothesized that germline variants in the major EMT regulatory genes (SNAIL1, ZEB1, ZEB2, TWIST1) may influence the development of HBV-related HCC...

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Detalles Bibliográficos
Autores principales: Liu, Wen-Xuan, Yang, Lei, Yan, Hui-Min, Yan, Li-Na, Zhang, Xiao-Lin, Ma, Ning, Tang, Long-Mei, Gao, Xia, Liu, Dian-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226114/
https://www.ncbi.nlm.nih.gov/pubmed/34178612
http://dx.doi.org/10.3389/fonc.2021.564477