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Solubility Controlling Peptide Tags of Opposite Charges Generate a Bivalent Immune Response Against Dengue ED3 Serotypes 3 and 4

We previously demonstrated that a protein’s immunogenicity could be substantially increased by attaching a hydrophobic solubility controlling peptide tag (SCP-tag) producing small sub-visible aggregates. Here, we report the oligomerization of Dengue envelop protein domain 3 (ED3), and consequently,...

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Detalles Bibliográficos
Autores principales: Rahman, Nafsoon, Miura, Shiho, Okawa, Mami, Kibria, Md. Golam, Islam, Mohammad Monirul, Kuroda, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226127/
https://www.ncbi.nlm.nih.gov/pubmed/34177912
http://dx.doi.org/10.3389/fimmu.2021.671590