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Thermodynamic Origin of Differential Excipient-Lysozyme Interactions
Understanding the intricate interplay of interactions between proteins, excipients, ions and water is important to achieve the effective purification and stable formulation of protein therapeutics. The free energy of lysozyme interacting with two kinds of polyanionic excipients, citrate and tripolyp...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226134/ https://www.ncbi.nlm.nih.gov/pubmed/34179093 http://dx.doi.org/10.3389/fmolb.2021.689400 |