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Thermodynamic Origin of Differential Excipient-Lysozyme Interactions

Understanding the intricate interplay of interactions between proteins, excipients, ions and water is important to achieve the effective purification and stable formulation of protein therapeutics. The free energy of lysozyme interacting with two kinds of polyanionic excipients, citrate and tripolyp...

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Detalles Bibliográficos
Autores principales:	Kalayan, Jas, Curtis, Robin A., Warwicker, Jim, Henchman, Richard H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226134/ https://www.ncbi.nlm.nih.gov/pubmed/34179093 http://dx.doi.org/10.3389/fmolb.2021.689400

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