Targeting the MYC Ubiquitination-Proteasome Degradation Pathway for Cancer Therapy

Deregulated MYC overexpression and activation contributes to tumor growth and progression. Given the short half-life and unstable nature of the MYC protein, it is not surprising that the oncoprotein is highly regulated via diverse posttranslational mechanisms. Among them, ubiquitination dynamically...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Xiao-Xin, Li, Yanping, Sears, Rosalie C., Dai, Mu-Shui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226175/
https://www.ncbi.nlm.nih.gov/pubmed/34178666
http://dx.doi.org/10.3389/fonc.2021.679445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226175/
https://www.ncbi.nlm.nih.gov/pubmed/34178666
http://dx.doi.org/10.3389/fonc.2021.679445

Ejemplares similares