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Targeting the MYC Ubiquitination-Proteasome Degradation Pathway for Cancer Therapy

Deregulated MYC overexpression and activation contributes to tumor growth and progression. Given the short half-life and unstable nature of the MYC protein, it is not surprising that the oncoprotein is highly regulated via diverse posttranslational mechanisms. Among them, ubiquitination dynamically...

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Detalles Bibliográficos
Autores principales:	Sun, Xiao-Xin, Li, Yanping, Sears, Rosalie C., Dai, Mu-Shui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226175/ https://www.ncbi.nlm.nih.gov/pubmed/34178666 http://dx.doi.org/10.3389/fonc.2021.679445

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