Interactive rather than independent effect of APOE and sex potentiates tau deposition in women

The apolipoprotein E gene (APOE) is the most important genetic risk factor for sporadic Alzheimer disease, with the ε4 allele being associated with increased cerebral amyloid-β and tau pathologies. Although APOE has been suggested to have a stronger effect in women as compared to men, there is a lac...

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Detalles Bibliográficos
Autores principales: Wang, Yi-Ting T, Pascoal, Tharick A, Therriault, Joseph, Kang, Min Su, Benedet, Andréa L, Savard, Melissa, Tissot, Cécile, Lussier, Firoza Z, Arias, Jaime Fernandez, Mathotaarachchi, Sulantha, Rajah, Maria Natasha, Gauthier, Serge, Rosa-Neto, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226193/
https://www.ncbi.nlm.nih.gov/pubmed/34189460
http://dx.doi.org/10.1093/braincomms/fcab126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226193/
https://www.ncbi.nlm.nih.gov/pubmed/34189460
http://dx.doi.org/10.1093/braincomms/fcab126

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