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Varied Contribution of Phospholipid Shedding From Membrane to Daptomycin Tolerance in Staphylococcus aureus

It has been suggested that daptomycin can be inactivated by lipids released by Staphylococcus aureus and that this effect is antagonized by phenol soluble modulins (PSMs), which bind to the shed lipids. PSM production is regulated by the Agr system, and others have shown that loss of the Agr functio...

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Detalles Bibliográficos
Autores principales: Shen, Tianwei, Hines, Kelly M., Ashford, Nathaniel K., Werth, Brian J., Xu, Libin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226217/
https://www.ncbi.nlm.nih.gov/pubmed/34179085
http://dx.doi.org/10.3389/fmolb.2021.679949