Ectopic Expression of TRIM25 Restores RIG-I Expression and IFN Production Reduced by Multiple Enteroviruses 3C(pro)

Enteroviruses (EVs) 3C proteins suppress type I interferon (IFN) responses mediated by retinoid acid-inducible gene I (RIG-I), while an E3 ubiquitin ligase, tripartite motif protein 25 (TRIM25)-mediated RIG-I ubiquitination is essential for RIG-I antiviral activity. Therefore, whether the effect of...

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Detalles Bibliográficos
Autores principales: Xiao, Huimin, Li, Jingliang, Yang, Xu, Li, Zhaolong, Wang, Ying, Rui, Yajuan, Liu, Bin, Zhang, Wenyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226358/
https://www.ncbi.nlm.nih.gov/pubmed/34170466
http://dx.doi.org/10.1007/s12250-021-00410-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226358/
https://www.ncbi.nlm.nih.gov/pubmed/34170466
http://dx.doi.org/10.1007/s12250-021-00410-x

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