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Design, Syntheses, and Bioevaluations of Some Novel N(2)-Acryloylbenzohydrazides as Chemostimulants and Cytotoxic Agents

A series of novel N(2)-acryloylhydrazides 1a–m and a related series of compounds 6a–c were prepared as potential chemostimulants. In general, these compounds are cytotoxic to human HCT 116 colon cancer cells, as well as human MCF-7 and MDA-MB-231 breast cancer cell lines. A representative compound N...

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Detalles Bibliográficos
Autores principales: Lakhani, Kinjal, Borrego, Edgar A., Cano, Karla G., Dimmock, Jonathan R., Aguilera, Renato J., Das, Swagatika, Roayapalley, Praveen K., Sharma, Rajendra K., Das, Umashankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226474/
https://www.ncbi.nlm.nih.gov/pubmed/34205029
http://dx.doi.org/10.3390/medicines8060027