Targeting Mitochondrial Damage as a Therapeutic for Ileal Crohn’s Disease

Paneth cell defects in Crohn’s disease (CD) patients (called the Type I phenotype) are associated with worse clinical outcomes. Recent studies have implicated mitochondrial dysfunction in Paneth cells as a mediator of ileitis in mice. We hypothesized that CD Paneth cells exhibit impaired mitochondri...

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Detalles Bibliográficos
Autores principales: Alula, Kibrom M., Jackson, Dakota N., Smith, Andrew D., Kim, Daniel S., Turner, Kevin, Odstrcil, Elizabeth, Kaipparettu, Benny A., Dassopoulos, Themistocles, Venuprasad, K., Feagins, Linda A., Theiss, Arianne L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226558/
https://www.ncbi.nlm.nih.gov/pubmed/34072441
http://dx.doi.org/10.3390/cells10061349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226558/
https://www.ncbi.nlm.nih.gov/pubmed/34072441
http://dx.doi.org/10.3390/cells10061349

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