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Modulation of PARP-1 Activity in a Broad Time Window Attenuates Memorizing Fear

The amygdala plays a critical role in the acquisition and consolidation of fear-related memories. Recent studies have demonstrated that ADP-ribosylation of histones, accelerated by PARPs, affects the chromatin structure and the binding of chromatin remodeling complexes with transcription factors. In...

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Detalles Bibliográficos
Autores principales: Elharrar, Einat, Dikshtein, Yahav, Meninger-Mordechay, Sapir, Lichtenstein, Yehuda, Yadid, Gal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226584/
https://www.ncbi.nlm.nih.gov/pubmed/34201014
http://dx.doi.org/10.3390/ijms22126170