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Modulation of PARP-1 Activity in a Broad Time Window Attenuates Memorizing Fear
The amygdala plays a critical role in the acquisition and consolidation of fear-related memories. Recent studies have demonstrated that ADP-ribosylation of histones, accelerated by PARPs, affects the chromatin structure and the binding of chromatin remodeling complexes with transcription factors. In...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226584/ https://www.ncbi.nlm.nih.gov/pubmed/34201014 http://dx.doi.org/10.3390/ijms22126170 |