Small-Molecule Inhibitors Targeting Proteasome-Associated Deubiquitinases

The 26S proteasome is the principal protease for regulated intracellular proteolysis. This multi-subunit complex is also pivotal for clearance of harmful proteins that are produced throughout the lifetime of eukaryotes. Recent structural and kinetic studies have revealed a multitude of conformationa...

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Detalles Bibliográficos
Autores principales: Moon, Seonghyeon, Muniyappan, Srinivasan, Lee, Sung-Bae, Lee, Byung-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226605/
https://www.ncbi.nlm.nih.gov/pubmed/34207520
http://dx.doi.org/10.3390/ijms22126213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226605/
https://www.ncbi.nlm.nih.gov/pubmed/34207520
http://dx.doi.org/10.3390/ijms22126213

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