Inhibition of Hsp90 Counteracts the Established Experimental Dermal Fibrosis Induced by Bleomycin

Our previous study demonstrated that heat shock protein 90 (Hsp90) is overexpressed in the involved skin of patients with systemic sclerosis (SSc) and in experimental dermal fibrosis. Pharmacological inhibition of Hsp90 prevented the stimulatory effects of transforming growth factor-beta on collagen...

Descripción completa

Detalles Bibliográficos
Autores principales: Štorkánová, Hana, Štorkánová, Lenka, Navrátilová, Adéla, Bečvář, Viktor, Hulejová, Hana, Oreská, Sabína, Heřmánková, Barbora, Špiritović, Maja, Bečvář, Radim, Pavelka, Karel, Vencovský, Jiří, Distler, Jörg H. W., Šenolt, Ladislav, Tomčík, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226767/
https://www.ncbi.nlm.nih.gov/pubmed/34200311
http://dx.doi.org/10.3390/biomedicines9060650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226767/
https://www.ncbi.nlm.nih.gov/pubmed/34200311
http://dx.doi.org/10.3390/biomedicines9060650

Ejemplares similares