RT-QuIC Using C-Terminally Truncated α-Synuclein Forms Detects Differences in Seeding Propensity of Different Brain Regions from Synucleinopathies

Aggregated α-synuclein (αSyn) protein is a core pathological feature of Parkinson’s disease (PD) and dementia with Lewy bodies (DLB). Both PD and DLB demonstrate the presence of diverse intracellular α-synuclein (αSyn) species, including C-terminally truncated αSyn (C-αSyn), although it is unknown h...

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Detalles Bibliográficos
Autores principales: Poggiolini, Ilaria, Erskine, Daniel, Vaikath, Nishant N., Ponraj, Janarthanan, Mansour, Said, Morris, Christopher M., El-Agnaf, Omar M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226794/
https://www.ncbi.nlm.nih.gov/pubmed/34072869
http://dx.doi.org/10.3390/biom11060820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226794/
https://www.ncbi.nlm.nih.gov/pubmed/34072869
http://dx.doi.org/10.3390/biom11060820

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