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RT-QuIC Using C-Terminally Truncated α-Synuclein Forms Detects Differences in Seeding Propensity of Different Brain Regions from Synucleinopathies

Aggregated α-synuclein (αSyn) protein is a core pathological feature of Parkinson’s disease (PD) and dementia with Lewy bodies (DLB). Both PD and DLB demonstrate the presence of diverse intracellular α-synuclein (αSyn) species, including C-terminally truncated αSyn (C-αSyn), although it is unknown h...

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Detalles Bibliográficos
Autores principales:	Poggiolini, Ilaria, Erskine, Daniel, Vaikath, Nishant N., Ponraj, Janarthanan, Mansour, Said, Morris, Christopher M., El-Agnaf, Omar M. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226794/ https://www.ncbi.nlm.nih.gov/pubmed/34072869 http://dx.doi.org/10.3390/biom11060820

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