Bacterial Cyclic Dinucleotides and the cGAS–cGAMP–STING Pathway: A Role in Periodontitis?

Host cells can recognize cytosolic double-stranded DNAs and endogenous second messengers as cyclic dinucleotides—including c-di-GMP, c-di-AMP, and cGAMP—of invading microbes via the critical and essential innate immune signaling adaptor molecule known as STING. This recognition activates the innate...

Descripción completa

Detalles Bibliográficos
Autores principales: Elmanfi, Samira, Yilmaz, Mustafa, Ong, Wilson W. S., Yeboah, Kofi S., Sintim, Herman O., Gürsoy, Mervi, Könönen, Eija, Gürsoy, Ulvi K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226932/
https://www.ncbi.nlm.nih.gov/pubmed/34070809
http://dx.doi.org/10.3390/pathogens10060675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226932/
https://www.ncbi.nlm.nih.gov/pubmed/34070809
http://dx.doi.org/10.3390/pathogens10060675

Ejemplares similares