Characterization and Pharmacological Inhibition of the Pore-Forming Clostridioides difficile CDTb Toxin

The clinically highly relevant Clostridioides (C.) difficile releases several AB-type toxins that cause diseases such as diarrhea and pseudomembranous colitis. In addition to the main virulence factors Rho/Ras-glycosylating toxins TcdA and TcdB, hypervirulent strains produce the binary AB-type toxin...

Descripción completa

Detalles Bibliográficos
Autores principales: Ernst, Katharina, Landenberger, Marc, Nieland, Julian, Nørgaard, Katharina, Frick, Manfred, Fois, Giorgio, Benz, Roland, Barth, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226936/
https://www.ncbi.nlm.nih.gov/pubmed/34071730
http://dx.doi.org/10.3390/toxins13060390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226936/
https://www.ncbi.nlm.nih.gov/pubmed/34071730
http://dx.doi.org/10.3390/toxins13060390

Ejemplares similares