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Characterization and Pharmacological Inhibition of the Pore-Forming Clostridioides difficile CDTb Toxin

The clinically highly relevant Clostridioides (C.) difficile releases several AB-type toxins that cause diseases such as diarrhea and pseudomembranous colitis. In addition to the main virulence factors Rho/Ras-glycosylating toxins TcdA and TcdB, hypervirulent strains produce the binary AB-type toxin...

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Detalles Bibliográficos
Autores principales:	Ernst, Katharina, Landenberger, Marc, Nieland, Julian, Nørgaard, Katharina, Frick, Manfred, Fois, Giorgio, Benz, Roland, Barth, Holger
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226936/ https://www.ncbi.nlm.nih.gov/pubmed/34071730 http://dx.doi.org/10.3390/toxins13060390

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