Application of Deep Neural Networks as a Prescreening Tool to Assign Individualized Absorption Models in Pharmacokinetic Analysis

A specific model for drug absorption is necessarily assumed in pharmacokinetic (PK) analyses following extravascular dosing. Unfortunately, an inappropriate absorption model may force other model parameters to be poorly estimated. An added complexity arises in population PK analyses when different i...

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Detalles Bibliográficos
Autores principales: Jaber, Mutaz M., Yaman, Burhaneddin, Sarafoglou, Kyriakie, Brundage, Richard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227048/
https://www.ncbi.nlm.nih.gov/pubmed/34073609
http://dx.doi.org/10.3390/pharmaceutics13060797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227048/
https://www.ncbi.nlm.nih.gov/pubmed/34073609
http://dx.doi.org/10.3390/pharmaceutics13060797

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