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Application of Deep Neural Networks as a Prescreening Tool to Assign Individualized Absorption Models in Pharmacokinetic Analysis
A specific model for drug absorption is necessarily assumed in pharmacokinetic (PK) analyses following extravascular dosing. Unfortunately, an inappropriate absorption model may force other model parameters to be poorly estimated. An added complexity arises in population PK analyses when different i...
Autores principales: | Jaber, Mutaz M., Yaman, Burhaneddin, Sarafoglou, Kyriakie, Brundage, Richard C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227048/ https://www.ncbi.nlm.nih.gov/pubmed/34073609 http://dx.doi.org/10.3390/pharmaceutics13060797 |
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