Binding of SARS-CoV Covalent Non-Covalent Inhibitors to the SARS-CoV-2 Papain-Like Protease and Ovarian Tumor Domain Deubiquitinases

The urgent need for novel and effective drugs against the SARS-CoV-2 coronavirus pandemic has stimulated research worldwide. The Papain-like protease (PLpro), which is essential for viral replication, shares a similar active site structural architecture to other cysteine proteases. Here, we have use...

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Detalles Bibliográficos
Autores principales: Sivakumar, Dakshinamurthy, Stein, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227062/
https://www.ncbi.nlm.nih.gov/pubmed/34071582
http://dx.doi.org/10.3390/biom11060802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227062/
https://www.ncbi.nlm.nih.gov/pubmed/34071582
http://dx.doi.org/10.3390/biom11060802

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