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Favipiravir (T-705) Protects IFNAR(−/−) Mice against Lethal Zika Virus Infection in a Sex-Dependent Manner

Zika virus (ZIKV), a member of the Flaviviridae family, is an important human pathogen that has caused epidemics in Africa, Southeast Asia, and the Americas. No licensed treatments for ZIKV disease are currently available. Favipiravir (T-705; 6-fluoro-3-hydroxy-2-pyrazinecarboxamide) and ribavirin (...

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Detalles Bibliográficos
Autores principales: Matz, Keesha, Emanuel, Jackson, Callison, Julie, Gardner, Don, Rosenke, Rebecca, Mercado-Hernandez, Reinaldo, Williamson, Brandi N., Feldmann, Heinz, Marzi, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227069/
https://www.ncbi.nlm.nih.gov/pubmed/34072604
http://dx.doi.org/10.3390/microorganisms9061178