TNFα-Induced LDL Cholesterol Accumulation Involve Elevated LDLR Cell Surface Levels and SR-B1 Downregulation in Human Arterial Endothelial Cells

Excess lipid droplets are frequently observed in arterial endothelial cells at sites of advanced atherosclerotic plaques. Here, the role of tumor necrosis factor alpha (TNFα) in modulating the low-density lipoprotein (LDL) content in confluent primary human aortic endothelial cells (pHAECs) was inve...

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Detalles Bibliográficos
Autor principal: Okoro, Emmanuel Ugochukwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227244/
https://www.ncbi.nlm.nih.gov/pubmed/34207810
http://dx.doi.org/10.3390/ijms22126236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227244/
https://www.ncbi.nlm.nih.gov/pubmed/34207810
http://dx.doi.org/10.3390/ijms22126236

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