Cargando…

Functional Characterization of the Dopaminergic Psychostimulant Sydnocarb as an Allosteric Modulator of the Human Dopamine Transporter

The dopamine transporter (DAT) serves a critical role in controlling dopamine (DA)-mediated neurotransmission by regulating the clearance of DA from the synapse and extrasynaptic regions and thereby modulating DA action at postsynaptic DA receptors. Major drugs of abuse such as amphetamine and cocai...

Descripción completa

Detalles Bibliográficos
Autores principales: Aggarwal, Shaili, Cheng, Mary Hongying, Salvino, Joseph M., Bahar, Ivet, Mortensen, Ole Valente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227285/
https://www.ncbi.nlm.nih.gov/pubmed/34199621
http://dx.doi.org/10.3390/biomedicines9060634