Further Evidence That Defects in Main Thyroid Dysgenesis-Related Genes Are an Uncommon Etiology for Primary Congenital Hypothyroidism in Mexican Patients: Report of Rare Variants in FOXE1, NKX2-5 and TSHR

Mexico shows a high birth prevalence of congenital hypothyroidism (CH) due to thyroid dysgenesis (TD). PAX8 defects underlie only 1% of these cases and NKX2-1 does not seem to be involved. Here, we analyzed other TD-related genes in 128 non-related Mexican patients (females 77.3%; 6 months to 16.6 y...

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Detalles Bibliográficos
Autores principales: Alcántara-Ortigoza, Miguel Angel, Sánchez-Verdiguel, Iraís, Fernández-Hernández, Liliana, Enríquez-Flores, Sergio, González-Núñez, Aidy, Hernández-Martínez, Nancy Leticia, Sánchez, Carmen, González-del Angel, Ariadna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227333/
https://www.ncbi.nlm.nih.gov/pubmed/34070861
http://dx.doi.org/10.3390/children8060457

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227333/
https://www.ncbi.nlm.nih.gov/pubmed/34070861
http://dx.doi.org/10.3390/children8060457

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