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Adverse Impact of DNA Methylation Regulatory Gene Mutations on the Prognosis of AML Patients in the 2017 ELN Favorable Risk Group, Particularly Those Defined by NPM1 Mutation

The 2017 ELN risk stratification has been widely adopted, but some studies have suggested the outcomes are heterogenous within the ELN risk groups and may be affected by other co-existing genetic mutations. This study evaluated the impact of DNA methylation regulatory gene (TET2, IDH1/2, DNMT3A, SET...

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Detalles Bibliográficos
Autores principales: Yu, James, Sun, Jingxin, Du, Yuan, Patel, Rushang, Varela, Juan Carlos, Mori, Shahram, Chang, Chung-Che
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227437/
https://www.ncbi.nlm.nih.gov/pubmed/34072516
http://dx.doi.org/10.3390/diagnostics11060986