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MYC-Induced Replicative Stress: A Double-Edged Sword for Cancer Development and Treatment
MYC is a transcription factor that controls the expression of a large fraction of cellular genes linked to cell cycle progression, metabolism and differentiation. MYC deregulation in tumors leads to its pervasive genome-wide binding of both promoters and distal regulatory regions, associated with se...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227504/ https://www.ncbi.nlm.nih.gov/pubmed/34201047 http://dx.doi.org/10.3390/ijms22126168 |