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Spatiotemporal 22q11.21 Protein Network Implicates DGCR8-Dependent MicroRNA Biogenesis as a Risk for Late Fetal Cortical Development in Psychiatric Diseases

The chromosome 22q11.21 copy number variant (CNV) is a vital risk factor that can be a genetic predisposition to neurodevelopmental disorders (NDD). As the 22q11.21 CNV affects multiple genes, causal disease genes and mechanisms affected are still poorly understood. Thus, we aimed to identify the mo...

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Detalles Bibliográficos
Autores principales: Chen, Liang, Cai, Wenxiang, Wang, Weidi, Liu, Zhe, Lin, Guan-Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227527/
https://www.ncbi.nlm.nih.gov/pubmed/34073122
http://dx.doi.org/10.3390/life11060514