Cargando…

Rational Design of Poly(disulfide)s as a Universal Platform for Delivery of CRISPR-Cas9 Machineries toward Therapeutic Genome Editing

[Image: see text] We synthesized a series of poly(disulfide)s by ring-opening polymerization and demonstrated that the copolymerization of monomer 1 containing diethylenetriamine moieties and monomer 2 containing guanidyl ligands could generate an efficient delivery platform for different forms of C...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guo, Jiajing, Wan, Tao, Li, Bowen, Pan, Qi, Xin, Huhu, Qiu, Yayu, Ping, Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227594/ https://www.ncbi.nlm.nih.gov/pubmed/34235260 http://dx.doi.org/10.1021/acscentsci.0c01648

Ejemplares similares

A dual-specific CRISPR-Cas nanosystem for precision therapeutic editing of liver disorders
por: Xu, Xiaojie, et al.
Publicado: (2022)

Genome-editing prodrug: Targeted delivery and conditional stabilization of CRISPR-Cas9 for precision therapy of inflammatory disease
por: Yan, Xiaojie, et al.
Publicado: (2021)

Heritable Genome Editing with CRISPR/Cas9 in the Silkworm, Bombyx mori
por: Wei, Wei, et al.
Publicado: (2014)

Harnessing heterologous and endogenous CRISPR-Cas machineries for efficient markerless genome editing in Clostridium
por: Pyne, Michael E., et al.
Publicado: (2016)

Delivery Platforms for CRISPR/Cas9 Genome Editing of Glial Cells in the Central Nervous System
por: Meneghini, Vasco, et al.
Publicado: (2021)

Delivery Aspects of CRISPR/Cas for in Vivo Genome Editing
por: Wilbie, Danny, et al.
Publicado: (2019)

Nanoparticle Delivery of CRISPR/Cas9 for Genome Editing
por: Duan, Li, et al.
Publicado: (2021)

Strategies in the delivery of Cas9 ribonucleoprotein for CRISPR/Cas9 genome editing
por: Zhang, Song, et al.
Publicado: (2021)

Nanovesicle-Mediated Delivery Systems for CRISPR/Cas Genome Editing
por: Kim, Dongyoon, et al.
Publicado: (2020)

A DNA-Free Editing Platform for Genetic Screens in Soybean via CRISPR/Cas9 Ribonucleoprotein Delivery
por: Subburaj, Saminathan, et al.
Publicado: (2022)

Rational guide RNA engineering for small-molecule control of CRISPR/Cas9 and gene editing
por: Liu, Xingyu, et al.
Publicado: (2022)

A Biophysical Model of CRISPR/Cas9 Activity for Rational Design of Genome Editing and Gene Regulation
por: Farasat, Iman, et al.
Publicado: (2016)

Rational engineering of a modular bacterial CRISPR–Cas activation platform with expanded target range
por: Villegas Kcam, Maria Claudia, et al.
Publicado: (2021)

CRISPR/dCas9 platforms in plants: strategies and applications beyond genome editing
por: Moradpour, Mahdi, et al.
Publicado: (2019)

Universal theranostic CRISPR/Cas13a RNA-editing system for glioma
por: Wu, Ye, et al.
Publicado: (2023)

CRISPR/Cas9 Delivery System Engineering for Genome Editing in Therapeutic Applications
por: Cheng, Hao, et al.
Publicado: (2021)

Lipid-Nanoparticle-Based Delivery of CRISPR/Cas9 Genome-Editing Components
por: Kazemian, Pardis, et al.
Publicado: (2022)

Recent advances in the delivery and applications of nonviral CRISPR/Cas9 gene editing
por: Sinclair, Frazer, et al.
Publicado: (2023)

Nanodevices for the Efficient Codelivery of CRISPR-Cas9 Editing Machinery and an Entrapped Cargo: A Proposal for Dual Anti-Inflammatory Therapy
por: García-Fernández, Alba, et al.
Publicado: (2022)

CRISPR-Cas9 DNA Base-Editing and Prime-Editing
por: Kantor, Ariel, et al.
Publicado: (2020)

Carboxylated branched poly(β-amino ester) nanoparticles enable robust cytosolic protein delivery and CRISPR-Cas9 gene editing
por: Rui, Yuan, et al.
Publicado: (2019)

Rationally Designed Anti-CRISPR Nucleic Acid Inhibitors of CRISPR-Cas9
por: Barkau, Christopher L., et al.
Publicado: (2019)

Strategies for delivery of CRISPR/Cas-mediated genome editing to obtain edited plants directly without transgene integration
por: Kocsisova, Zuzana, et al.
Publicado: (2023)

Commentary: RNA editing with CRISPR-Cas13
por: Matsoukas, Ianis G.
Publicado: (2018)

Genome Editing in Bacteria: CRISPR-Cas and Beyond
por: Arroyo-Olarte, Ruben D., et al.
Publicado: (2021)

CRISPR/Cas9 or prime editing? – It depends on…
por: Schenke, Dirk
Publicado: (2020)

CRISPR/Cas9 Delivery Mediated with Hydroxyl‐Rich Nanosystems for Gene Editing in Aorta
por: Zhang, Xiaoping, et al.
Publicado: (2019)

Baculoviral delivery of CRISPR/Cas9 facilitates efficient genome editing in human cells
por: Hindriksen, Sanne, et al.
Publicado: (2017)

CRISPR-Cas12a delivery by DNA-mediated bioresponsive editing for cholesterol regulation
por: Sun, Wujin, et al.
Publicado: (2020)

Stimulus-Responsive Smart Nanoparticles-Based CRISPR-Cas Delivery for Therapeutic Genome Editing
por: Naeem, Muhammad, et al.
Publicado: (2021)

Delivery strategies for CRISPR/Cas genome editing tool for retinal dystrophies: challenges and opportunities
por: Lohia, Aayushi, et al.
Publicado: (2022)

Allele-specific genome editing and correction of disease-associated phenotypes in rats using the CRISPR–Cas platform
por: Yoshimi, K., et al.
Publicado: (2014)

CRISPR/Cas9 genome-edited universal CAR T cells in patients with relapsed/refractory lymphoma
por: Guo, Yelei, et al.
Publicado: (2022)

Engineering RNA Virus Interference via the CRISPR/Cas13 Machinery in Arabidopsis
por: Aman, Rashid, et al.
Publicado: (2018)

Potential Use of CRISPR/Cas13 Machinery in Understanding Virus–Host Interaction
por: Bayoumi, Mahmoud, et al.
Publicado: (2021)

Guanidyl-Rich Poly(β Amino Ester)s for Universal Functional Cytosolic Protein Delivery and Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) Cas9 Ribonucleoprotein Based Gene Editing
por: Wang, Xianqing, et al.
Publicado: (2023)

Targeted delivery of CRISPR-Cas9 ribonucleoprotein into arthropod ovaries for heritable germline gene editing
por: Chaverra-Rodriguez, Duverney, et al.
Publicado: (2018)

Systemic nanoparticle delivery of CRISPR-Cas9 ribonucleoproteins for effective tissue specific genome editing
por: Wei, Tuo, et al.
Publicado: (2020)

Virus-Like Particle Mediated CRISPR/Cas9 Delivery for Efficient and Safe Genome Editing
por: Lyu, Pin, et al.
Publicado: (2020)

Lentiviral Vectors for Delivery of Gene-Editing Systems Based on CRISPR/Cas: Current State and Perspectives
por: Dong, Wendy, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_4pqn624inc64bqrh4ov7llg1s1