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A Simple, Accurate and Cost-Effective Capillary Electrophoresis Test with Computational Methods to Aid in Universal Microsatellite Instability Testing

Background: Microsatellite instability (MSI) testing is important for the classification of Lynch syndrome, as a prognostic marker and as a guide for adjuvant chemotherapy in colorectal cancer (CRC). The gold standard for determining MSI status has traditionally been fluorescent multiplex polymerase...

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Detalles Bibliográficos
Autores principales: Toh, James Wei Tatt, Singh, Puneet, Tangirala, Venkata A. A. S. K., Limmer, Alex, Spring, Kevin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227602/
https://www.ncbi.nlm.nih.gov/pubmed/34198876
http://dx.doi.org/10.3390/cells10061401