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Nucleoside Analogues Are Potent Inducers of Pol V-mediated Mutagenesis

Drugs targeting DNA and RNA in mammalian cells or viruses can also affect bacteria present in the host and thereby induce the bacterial SOS system. This has the potential to increase mutagenesis and the development of antimicrobial resistance (AMR). Here, we have examined nucleoside analogues (NAs)...

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Detalles Bibliográficos
Autores principales: Sumabe, Balagra Kasim, Ræder, Synnøve Brandt, Røst, Lisa Marie, Sharma, Animesh, Donkor, Eric S., Mosi, Lydia, Duodu, Samuel, Bruheim, Per, Otterlei, Marit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227612/
https://www.ncbi.nlm.nih.gov/pubmed/34198819
http://dx.doi.org/10.3390/biom11060843