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MyD88 Is Not Required for Muscle Injury-Induced Endochondral Heterotopic Ossification in a Mouse Model of Fibrodysplasia Ossificans Progressiva

Excess inflammation and canonical BMP receptor (BMPR) signaling are coinciding hallmarks of the early stages of injury-induced endochondral heterotopic ossification (EHO), especially in the rare genetic disease fibrodysplasia ossificans progressiva (FOP). Multiple inflammatory signaling pathways can...

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Detalles Bibliográficos
Autores principales: Lyu, Huili, Elkins, Cody M., Pierce, Jessica L., Serezani, C. Henrique, Perrien, Daniel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227787/
https://www.ncbi.nlm.nih.gov/pubmed/34206078
http://dx.doi.org/10.3390/biomedicines9060630