The Core Stem Genes SOX2, POU5F1/OCT4, and NANOG Are Expressed in Human Parathyroid Tumors and Modulated by MEN1, YAP1, and β-catenin Pathways Activation

Tumors of the parathyroid glands are the second most common endocrine neoplasia. Epigenetic studies revealed an embryonic signature involved in parathyroid tumorigenesis. Here, we investigated the expression of the stem core genes SOX2, POU5F1/OCT4, and NANOG. Rare cells within normal parathyroid gl...

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Detalles Bibliográficos
Autores principales: Verdelli, Chiara, Morotti, Annamaria, Tavanti, Giulia Stefania, Silipigni, Rosamaria, Guerneri, Silvana, Ferrero, Stefano, Vicentini, Leonardo, Vaira, Valentina, Corbetta, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227846/
https://www.ncbi.nlm.nih.gov/pubmed/34199594
http://dx.doi.org/10.3390/biomedicines9060637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227846/
https://www.ncbi.nlm.nih.gov/pubmed/34199594
http://dx.doi.org/10.3390/biomedicines9060637

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