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The Core Stem Genes SOX2, POU5F1/OCT4, and NANOG Are Expressed in Human Parathyroid Tumors and Modulated by MEN1, YAP1, and β-catenin Pathways Activation
Tumors of the parathyroid glands are the second most common endocrine neoplasia. Epigenetic studies revealed an embryonic signature involved in parathyroid tumorigenesis. Here, we investigated the expression of the stem core genes SOX2, POU5F1/OCT4, and NANOG. Rare cells within normal parathyroid gl...
Autores principales: | Verdelli, Chiara, Morotti, Annamaria, Tavanti, Giulia Stefania, Silipigni, Rosamaria, Guerneri, Silvana, Ferrero, Stefano, Vicentini, Leonardo, Vaira, Valentina, Corbetta, Sabrina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227846/ https://www.ncbi.nlm.nih.gov/pubmed/34199594 http://dx.doi.org/10.3390/biomedicines9060637 |
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