Pt(II)-Thiocarbohydrazone Complex as Cytotoxic Agent and Apoptosis Inducer in Caov-3 and HT-29 Cells through the P53 and Caspase-8 Pathways

In this study, a platinum(II) complex ([Pt(H(2)L)(PPh(3))] complex) containing a thiocarbohydrazone as the ligand was tested as an anti-proliferative agent against ovarian adenocarcinoma (Caov-3) and human colorectal adenocarcinoma (HT-29) through MTT assays. Apoptotic markers were tested by the AO/...

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Detalles Bibliográficos
Autores principales: Ibrahim, Abeer A., Kareem, Mohanad M., Al-Noor, Taghreed H., Al-Muhimeed, Tahani, AlObaid, Abeer A., Albukhaty, Salim, Sulaiman, Ghassan M., Jabir, Majid, Taqi, Zainab J., Sahib, Usama I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227887/
https://www.ncbi.nlm.nih.gov/pubmed/34073459
http://dx.doi.org/10.3390/ph14060509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227887/
https://www.ncbi.nlm.nih.gov/pubmed/34073459
http://dx.doi.org/10.3390/ph14060509

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