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Intrinsic and Chemotherapeutic Stressors Modulate ABCC-Like Transport in Trypanosoma cruzi

Trypanosoma cruzi is the etiologic agent for Chagas disease, which affects 6–7 million people worldwide. The biological diversity of the parasite reflects on inefficiency of benznidazole, which is a first choice chemotherapy, on chronic patients. ABC transporters that extrude xenobiotics, metabolite...

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Detalles Bibliográficos
Autores principales: da Costa, Kelli Monteiro, Salustiano, Eduardo J., Valente, Raphael do Carmo, Freire-de-Lima, Leonardo, Mendonça-Previato, Lucia, Previato, José Osvaldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227891/
https://www.ncbi.nlm.nih.gov/pubmed/34207619
http://dx.doi.org/10.3390/molecules26123510