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Immunity-longevity tradeoff neurally controlled by GABAergic transcription factor PITX1/UNC-30
A body of evidence indicates that metazoan immune and aging pathways are largely interconnected, but the mechanisms involved in their homeostatic control remain unclear. In this study, we find that the PITX (paired-like homeodomain) transcription factor UNC-30 controls the tradeoff between immunity...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227953/ https://www.ncbi.nlm.nih.gov/pubmed/34038721 http://dx.doi.org/10.1016/j.celrep.2021.109187 |