Cargando…
Immunity-longevity tradeoff neurally controlled by GABAergic transcription factor PITX1/UNC-30
A body of evidence indicates that metazoan immune and aging pathways are largely interconnected, but the mechanisms involved in their homeostatic control remain unclear. In this study, we find that the PITX (paired-like homeodomain) transcription factor UNC-30 controls the tradeoff between immunity...
Autores principales: | Otarigho, Benson, Aballay, Alejandro |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227953/ https://www.ncbi.nlm.nih.gov/pubmed/34038721 http://dx.doi.org/10.1016/j.celrep.2021.109187 |
Ejemplares similares
-
Cholesterol Regulates Innate Immunity via Nuclear Hormone Receptor NHR-8
por: Otarigho, Benson, et al.
Publicado: (2020) -
Cholesterol Regulates Innate Immunity via Nuclear Hormone Receptor NHR-8
por: Otarigho, Benson, et al.
Publicado: (2021) -
Neuronal NPR-15 modulates molecular and behavioral immune responses via the amphid sensory neuron-intestinal axis in C. elegans
por: Otarigho, Benson, et al.
Publicado: (2023) -
The Bicoid Class Homeodomain Factors ceh-36/OTX and unc-30/PITX Cooperate in C. elegans Embryonic Progenitor Cells to Regulate Robust Development
por: Walton, Travis, et al.
Publicado: (2015) -
An antagonistic pleiotropic gene regulates the reproduction and longevity tradeoff
por: Wu, Dou, et al.
Publicado: (2022)