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Immunity-longevity tradeoff neurally controlled by GABAergic transcription factor PITX1/UNC-30

A body of evidence indicates that metazoan immune and aging pathways are largely interconnected, but the mechanisms involved in their homeostatic control remain unclear. In this study, we find that the PITX (paired-like homeodomain) transcription factor UNC-30 controls the tradeoff between immunity...

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Detalles Bibliográficos
Autores principales: Otarigho, Benson, Aballay, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227953/
https://www.ncbi.nlm.nih.gov/pubmed/34038721
http://dx.doi.org/10.1016/j.celrep.2021.109187

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