Oncogenic FGFR Fusions Produce Centrosome and Cilia Defects by Ectopic Signaling

A single primary cilium projects from most vertebrate cells to guide cell fate decisions. A growing list of signaling molecules is found to function through cilia and control ciliogenesis, including the fibroblast growth factor receptors (FGFR). Aberrant FGFR activity produces abnormal cilia with de...

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Detalles Bibliográficos
Autores principales: Nita, Alexandru, Abraham, Sara P., Krejci, Pavel, Bosakova, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227969/
https://www.ncbi.nlm.nih.gov/pubmed/34207779
http://dx.doi.org/10.3390/cells10061445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227969/
https://www.ncbi.nlm.nih.gov/pubmed/34207779
http://dx.doi.org/10.3390/cells10061445

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