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Oncogenic FGFR Fusions Produce Centrosome and Cilia Defects by Ectopic Signaling
A single primary cilium projects from most vertebrate cells to guide cell fate decisions. A growing list of signaling molecules is found to function through cilia and control ciliogenesis, including the fibroblast growth factor receptors (FGFR). Aberrant FGFR activity produces abnormal cilia with de...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227969/ https://www.ncbi.nlm.nih.gov/pubmed/34207779 http://dx.doi.org/10.3390/cells10061445 |