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Synthesis of Novel, Dual-Targeting (68)Ga-NODAGA-LacN-E[c(RGDfK)](2) Glycopeptide as a PET Imaging Agent for Cancer Diagnosis

Radiolabeled peptides possessing an Arg-Gly-Asp (RGD) motif are widely used radiopharmaceuticals for PET imaging of tumor angiogenesis due to their high affinity and selectivity to α(v)β(3) integrin. This receptor is overexpressed in tumor and tumor endothelial cells in the case of numerous cancer c...

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Detalles Bibliográficos
Autores principales: Gyuricza, Barbara, Szabó, Judit P., Arató, Viktória, Szücs, Dániel, Vágner, Adrienn, Szikra, Dezső, Fekete, Anikó
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227980/
https://www.ncbi.nlm.nih.gov/pubmed/34073528
http://dx.doi.org/10.3390/pharmaceutics13060796