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Synthesis of Novel, Dual-Targeting (68)Ga-NODAGA-LacN-E[c(RGDfK)](2) Glycopeptide as a PET Imaging Agent for Cancer Diagnosis
Radiolabeled peptides possessing an Arg-Gly-Asp (RGD) motif are widely used radiopharmaceuticals for PET imaging of tumor angiogenesis due to their high affinity and selectivity to α(v)β(3) integrin. This receptor is overexpressed in tumor and tumor endothelial cells in the case of numerous cancer c...
Autores principales: | Gyuricza, Barbara, Szabó, Judit P., Arató, Viktória, Szücs, Dániel, Vágner, Adrienn, Szikra, Dezső, Fekete, Anikó |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227980/ https://www.ncbi.nlm.nih.gov/pubmed/34073528 http://dx.doi.org/10.3390/pharmaceutics13060796 |
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