Somatic Functional Deletions of Upstream Open Reading Frame-Associated Initiation and Termination Codons in Human Cancer

Upstream open reading frame (uORF)-mediated translational control has emerged as an important regulatory mechanism in human health and disease. However, a systematic search for cancer-associated somatic uORF mutations has not been performed. Here, we analyzed the genetic variability at canonical (uA...

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Detalles Bibliográficos
Autores principales: Jürgens, Lara, Manske, Felix, Hubert, Elvira, Kischka, Tabea, Flötotto, Lea, Klaas, Oliver, Shabardina, Victoria, Schliemann, Christoph, Makalowski, Wojciech, Wethmar, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227997/
https://www.ncbi.nlm.nih.gov/pubmed/34072580
http://dx.doi.org/10.3390/biomedicines9060618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227997/
https://www.ncbi.nlm.nih.gov/pubmed/34072580
http://dx.doi.org/10.3390/biomedicines9060618

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