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Different Roles of p62 (SQSTM1) Isoforms in Keratin-Related Protein Aggregation

p62/Sequestosome-1 (p62) is a multifunctional adaptor protein and is also a constant component of disease-associated protein aggregates, including Mallory–Denk bodies (MDBs), in steatohepatitis and hepatocellular carcinoma. We investigated the interaction of the two human p62 isoforms, p62-H1 (full-...

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Detalles Bibliográficos
Autores principales: Somlapura, Meghana, Gottschalk, Benjamin, Lahiri, Pooja, Kufferath, Iris, Pabst, Daniela, Rülicke, Thomas, Graier, Wolfgang F., Denk, Helmut, Zatloukal, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227998/
https://www.ncbi.nlm.nih.gov/pubmed/34207662
http://dx.doi.org/10.3390/ijms22126227