Novel Pharmaceutical Strategy for Selective Abrogation of TSP1-Induced Vascular Dysfunction by Decoy Recombinant CD47 Soluble Receptor in Prophylaxis and Treatment Models

Elevated thrombospondin 1 (TSP1) is a prevalent factor, via cognate receptor CD47, in the pathogenesis of cardiovascular conditions, including ischemia-reperfusion injury (IRI) and pulmonary arterial hypertension (PAH). Moreover, TSP1/CD47 interaction has been found to be associated with platelet hy...

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Detalles Bibliográficos
Autores principales: Yao, Molly, Sturdivant, Jalicia, Ebrahimi, Aren, Ganguly, Samayita, Elbayoumi, Tamer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228143/
https://www.ncbi.nlm.nih.gov/pubmed/34205047
http://dx.doi.org/10.3390/biomedicines9060642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228143/
https://www.ncbi.nlm.nih.gov/pubmed/34205047
http://dx.doi.org/10.3390/biomedicines9060642

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