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Considerations in the Design of Non-Clinical Development Programmes to Support Non-Viral Genetically Modified Mesenchymal Stromal Cell Therapies

Due to their immune suppressive pharmacology, regenerative capacity, and immune privileged status, mesenchymal stromal cells (MSCs) are an attractive cell type to treat a variety of diseases. Genetically engineered MSCs are currently in non-clinical and clinical development for a wide range of appli...

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Detalles Bibliográficos
Autores principales: Iansante, Valeria, Brooks, Andrew, Coney, Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228211/
https://www.ncbi.nlm.nih.gov/pubmed/34199356
http://dx.doi.org/10.3390/pharmaceutics13060823