HERC5 and the ISGylation Pathway: Critical Modulators of the Antiviral Immune Response

Mammalian cells have developed an elaborate network of immunoproteins that serve to identify and combat viral pathogens. Interferon-stimulated gene 15 (ISG15) is a 15.2 kDa tandem ubiquitin-like protein (UBL) that is used by specific E1–E2–E3 ubiquitin cascade enzymes to interfere with the activity...

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Detalles Bibliográficos
Autores principales: Mathieu, Nicholas A., Paparisto, Ermela, Barr, Stephen D., Spratt, Donald E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228270/
https://www.ncbi.nlm.nih.gov/pubmed/34207696
http://dx.doi.org/10.3390/v13061102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228270/
https://www.ncbi.nlm.nih.gov/pubmed/34207696
http://dx.doi.org/10.3390/v13061102

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