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HERC5 and the ISGylation Pathway: Critical Modulators of the Antiviral Immune Response
Mammalian cells have developed an elaborate network of immunoproteins that serve to identify and combat viral pathogens. Interferon-stimulated gene 15 (ISG15) is a 15.2 kDa tandem ubiquitin-like protein (UBL) that is used by specific E1–E2–E3 ubiquitin cascade enzymes to interfere with the activity...
Autores principales: | Mathieu, Nicholas A., Paparisto, Ermela, Barr, Stephen D., Spratt, Donald E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228270/ https://www.ncbi.nlm.nih.gov/pubmed/34207696 http://dx.doi.org/10.3390/v13061102 |
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